Northlake Urology Group

Made in the USA, Ovasitol® provides inositols in a naturally balanced 40:1 ratio supplied as 4,000 mg of myo-inositol and 100 mg of D-chiro-inositol per day.  Inositol is synthesized from glucose in tissues throughout the body, being found in high concentration in the brain, where it may support neurotransmitter function.  Inositols function as insulin second messengers, helping to metabolize glucose and maintain normal blood sugar.  Legumes, grains, nuts, and fruits like oranges and cantaloupes are rich with inositols.  

Clinical research suggests a beneficial role for inositol supplementation, particularly in metabolic conditions involving insulin resistance:

• polycystic ovarian syndrome (PCOS) – a common condition characterized by enlarged cystic ovaries, irregular menstrual cycles, infertility, acne, and hirsutism

• metabolic syndrome – characterized by weight gain, truncal obesity, hypertension (high blood pressure), hyperlipidemia (high cholesterol), and hyperglycemia (elevated blood sugar)

• mood disorders – depression, anxiety, and panic disorder – (additional research required to confirm inositol’s possible role in combating mood disorders)

Obesity and metabolic syndrome appear to be increasing in the US.  An outspoken national public health advocate recently stated, "The more metformin they prescribe .. the more diabetes we have,” also stating, “regulatory agencies must stop hiding science from us when it clashes with the commercial ambitions of the pharmaceutical industry.” 

Have we become overly dependent on pharmaceuticals?  Prescription medications most certainly have an appropriate place in the hierarchy of treatments for chronic disease.  Yet, instinctive remedies like dietary improvements, exercise, and even natural supplements are critically important, perhaps not only in treatment, but possibly in prevention of some chronic disease.  Those interested in avoiding potential drug side-effects and drug interactions may be particularly motivated to consider alternative remedies.  

Perhaps the most studied benefit of inositol supplementation relates to polycystic ovary syndrome (PCOS).  PCOS is an endocrine disorder and leading cause of female infertility, affecting up to 15 percent of women of childbearing age.  According to the World Health Organization (WHO), PCOS is the most common cause of ovulation failure.  Despite the well documented prevalence of PCOS, the condition is estimated to be under-diagnosed in up to 70 percent of patients.  Thus, many women affected by PCOS remain undiagnosed.

Women with family histories of diabetes are at increased risk of developing PCOS.  WHO acknowledges that women with PCOS are also more prone to develop other serious health conditions including diabetes, hyperlipidemia (elevated cholesterol), hypertension (high blood pressure), heart disease, and possibly even endometrial (uterine) carcinoma.

PCOS is associated with irregular menstrual periods, excess androgen hormone secretion, abnormal facial hair growth (hirsutism), acne, belly fat (truncal obesity), insulin resistance (pre-diabetes), and ovarian cysts.  In PCOS, irregular periods are commonly associated with absent ovulation and resulting infertility.  Diagnostic criteria suggest that doctors consider PCOS in patients with two or more of these signs and symptoms.

Typical recommendations for treatment of PCOS include dietary restrictions, weight loss, and medications, depending upon the fertility desires of individual patients.  Metformin is an anti-diabetic drug used to treat PCOS, particularly in obese patients with insulin resistance (pre-diabetes).  However, metformin commonly causes unpleasant gastrointestinal side effects, frequently leading to discontinuation of the drug.  Clearly, other safe and effective treatments are needed. 

Fortunately, for many PCOS patients there may be an alternative.  Inositol supplementation has been shown to be effective, improving hormonal balance, metabolism, menstruation, and ovulation.  In a meta-analysis of 26 randomized controlled clinical research trials including over 1,600 patients, use of inositols resulted in greater normalization of menstrual cycles and normalization of blood sugar as compared to placebo.  By these measures, inositol supplementation was found to be equivalent to metformin in women with polycystic ovarian syndrome (PCOS) and insulin resistance.  Researchers agree that "Inositol is an effective and safe treatment in PCOS showing non-inferiority (statistical equivalence) in most outcomes as compared to the gold standard (established) treatment -- (that being) metformin.”

Researchers suggest that two particular molecular variations (isomers) of inositol may be critical second messengers for insulin in the metabolic processes of the body.  These critical isomers are myo-inositol and d-chiro-inositol.  In healthy ovaries, these inositol isomers are found in a 40:1 ratio (40 parts myo-inositol to one part d-chiro-inositol).  As recommended by an International Obstetrics and Gynecology Consensus Conference, Ovasitol® contains both of these important inositol isomers in precisely this same healthy 40:1 ratio.

Always follow the recommendations of your healthcare professional and never discontinue prescribed medications without the advice and direct oversight of your physician.  Ask your internist, family doctor, endocrinologist, or gynecologist about Ovasitol® inositols.  You may be pleasantly surprised by your doctor's response.

Ovasitol® is formulated as a powder to be mixed in hot or cold water (or any non-carbonated liquid) and may be ordered in your choice of either individual dose packets or as a multi-dose canister (with a scoop).

Click the picture for more information or to order.  When starting new medications or supplements, always check with your pharmacist about possible medication-supplement interactions.  Check with your physician about which supplement, medication, or diet / lifestyle change is right for you.  Also, read the FAQ information associated with this supplement and consider taking advantage of a free consultation with one of our registered Theralogix dietitians.

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Statements made herein have not been evaluated by the US Food and Drug Administration.  Product is not intended to diagnose, treat, cure, or prevent any disease.